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The 10 best tricks to begin packing for your vacation... .. start with these, that we hand picked from this simple list . 1: Roll clothes and pack them first. 2: Choose travel-friendly fabrics. 3: Pack the first outfit you'll want to wear on top. 4: Place heavy items at the base. 5: Layer plastic dry cleaning bags between clothes. 6: Use packing cubes. 7: Get an extra tote for souvenirs. 8: Bring two small laundry bags. 9: Organize your liquids bags. 10: Keep important medication in your purse.